What is the Difference Between Polynucleotides and Dermal Filler?

Claire Lavery • May 20, 2024

Polynucleotide treatments are one of the newest treatment options to become available, and they can essentially be viewed as a new variety of injectable treatment. But what are polynucleotides, and how do they differ from traditional dermal fillers?

An Introduction to Polynucleotide Treatments


Polynucleotide treatments are formulated from fragments of DNA extracted from salmon. When injected into the skin, this bio-stimulating treatment works to restore lost elasticity and firmness, soften fine lines and wrinkles, reduce hollowness, and protect against cellular damage and free radicals.


How Do Polynucleotides Work?


It can be helpful to view polynucleotides as a skin booster, as they essentially provide the skin with all the building blocks it needs to stimulate the production of collagen and fibroblasts, which are essential to the repair and regeneration of skin tissue.


Additionally, as chains of polynucleotides attract water molecules, they deliver a boost of restorative hydration, which contributes to improved elasticity and the process of counteracting skin damage from free radicals, stressors, and UV rays.


What Results Can I Expect From Polynucleotide Treatments?


As polynucleotides work to boost hydration, collagen production and skin elasticity, this type of super-charged moisturising treatment can be used both preventatively in younger skin and to rejuvenate ageing skin.


In addition to anti-ageing benefits, including reducing lines and wrinkles and restoring lost volume, the reparative properties of polynucleotides mean that this type of treatment can also be used to reduce the inflammation, irritation and redness caused by a range of skin conditions, including eczema, rosacea, hyperpigmentation, and acne.


Are Polynucleotides and Dermal Fillers the Same?


Although both dermal fillers and polynucleotide treatments are both injected into the skin, they are actually very different.


Dermal fillers are typically formulated with a high concentration of hyaluronic acid, which provides immediately visible results in the form of added contour, structure, volume and definition in the treatment area.


Conversely, while some polynucleotide treatments will provide a noticeable lift in the structure of the skin after just a few minutes, this type of treatment works to improve the quality of the skin, which means that you will continue to see improved results develop over a period of time.


Can Polynucleotides and Dermal Fillers Work Together?


Yes, both treatments can be used in conjunction with one another as part of a holistic skin treatment plan. Dermal fillers will provide instant results, while the polynucleotides get to work to provide long-lasting results that continue to improve over time.





If you are interested in learning more about Polynucleotides treatment or would like to arrange a consultation to determine whether it is the right treatment for you, please get in touch!


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